logo

korean english

게시판

Home > 게시판 > 세미나

아래와 같이 콜로퀴움을 개최하오니 많이 참석해 주시기 바랍니다. 4시 10분부터 2층 라운지세미나실에 다과를 준비하오니 많은 참석 부탁드립니다 아 래 제목: In vivo optical imaging of hemodynamic changes as a surrogate signal of neuronal activity in the neocortex 연사: 서 민 아 교수(성균관대학교 생명과학과) 일시: 2009년 5월 1일(금) 오후4:30 장소: 물리학과 세미나실(31355호실) 초록: Optical imaging offers excellent spatio-temporal sensitivity that is unparalleled by any other perfusion based imaging techniques. We used in vivo optical recording of intrinsic signals (ORIS) to map neurovascular hemodynamics of perfusion, oximetry and membrane potential during epileptic events in rat and mouse neocortex. Studies of hemodynamic changes with ORIS alone were also performed in human. Laboratory studies in rodent epilepsy models have demonstrated a persistent increase in deoxygenated hemoglobin (Hbr) and a decrease in tissue oxygenation during interictal spikes and ictal events. This “epileptic dip”, like the “initial dip” recorded during normal sensory processing, implies that the enormous rise in cerebral blood flow (CBF) is inadequate to meet the increased metabolic demands associated with synchronized epileptic activity. These findings are critically important to the interpretation of the perfusion-based imaging studies, such as fMRI. In addition, we visualized the effect of direct cortical electrical stimulation, an alterative epilepsy treatment. The optical data following direct cortical electrical stimulation showed that hemodynamic signals are sensitive to different electrical stimulation parameters. Furthermore, our recent data demonstrated that the application of unilateral electrical stimulation is able to elicit bilateral hemodynamic responses in rat neocortex. 자료를 다운 받으시려면 아래의 링크을 클릭해주세요. http://physics.skku.ac.kr/ppt/090501.ppt
번호 제목 날짜 조회 수
공지 2021학년도 1학기 콜로퀴움 일정 2021.01.13 27714
공지 <12/8(Thu.) 11:00am>노벨상 소개 강연 - 2016년 노벨 물리학상: 위상 응집 물리의 탄생 2016.11.28 635170
401 <11/7> On-Film Formation of Bi Nanowires with Extraordinary Electron Mobility 2008.11.03 65548
400 <11/14> 한방의료기기에서 나노소자의 활용 2008.11.11 59652
399 <11/21>Super B factory @ KEK 2008.11.19 60470
398 <11/28> 건국 100주년을 대비하는 과학청년의 자세 2008.11.25 59725
397 <12/5> Fluerenes with diversed structures and their applications 2008.12.02 67142
396 <12/12> 나노물리학과 컴퓨터 시뮬레이션 2008.12.08 60281
395 <3/13> Probing hidden magnetism and quantum criticality in unconventional superconductors 2009.03.06 68673
394 THINKING PHYSICS 발표회 2009.03.16 60821
393 <3/27>Social Experience, Brain, and Behavior 2009.03.23 67674
392 <4/3>Enhanced emission rate from a single quantum well using surface plasmon 2009.03.31 61220
391 <4/10> Holographic Nucleons: In Search of a String Theoretical Solution to QCD 2009.04.06 62286
390 <4/17>고온초전도 2세대 선재 : 현황 및 전망 2009.05.06 60880
» <5/1>In vivo optical imaging of hemodynamic changes 2009.05.06 81137
388 <5/8>Recent trend of thin film battery 2009.05.06 69981
387 <5/15>강상관 전자계의 열전변환 응용 2009.05.08 61599
386 <5/22> Semiconductor Nanomaterials for Unusual Format Electronics 2009.05.18 60112
385 <5/29> Nanomaterials Work at NASA-Johnson Space Center 2009.05.25 63761
384 <6/5>Magnetism and Superconductivity 2009.05.27 73821
383 <9/11> Complex networks in technology, biology and sociology 2009.09.04 65483
382 <9/18> 생체계에서의 협동현상: 박테리아 수영에서부터 고분자 수송현상까지 2009.09.14 60815