korean english


Home > 게시판 > 세미나

아래와 같이 콜로퀴움을 개최하오니 많이 참석해 주시기 바랍니다. 4시 10분부터 2층 라운지세미나실에 다과를 준비하오니 많은 참석 부탁드립니다 아 래 제목: In vivo optical imaging of hemodynamic changes as a surrogate signal of neuronal activity in the neocortex 연사: 서 민 아 교수(성균관대학교 생명과학과) 일시: 2009년 5월 1일(금) 오후4:30 장소: 물리학과 세미나실(31355호실) 초록: Optical imaging offers excellent spatio-temporal sensitivity that is unparalleled by any other perfusion based imaging techniques. We used in vivo optical recording of intrinsic signals (ORIS) to map neurovascular hemodynamics of perfusion, oximetry and membrane potential during epileptic events in rat and mouse neocortex. Studies of hemodynamic changes with ORIS alone were also performed in human. Laboratory studies in rodent epilepsy models have demonstrated a persistent increase in deoxygenated hemoglobin (Hbr) and a decrease in tissue oxygenation during interictal spikes and ictal events. This “epileptic dip”, like the “initial dip” recorded during normal sensory processing, implies that the enormous rise in cerebral blood flow (CBF) is inadequate to meet the increased metabolic demands associated with synchronized epileptic activity. These findings are critically important to the interpretation of the perfusion-based imaging studies, such as fMRI. In addition, we visualized the effect of direct cortical electrical stimulation, an alterative epilepsy treatment. The optical data following direct cortical electrical stimulation showed that hemodynamic signals are sensitive to different electrical stimulation parameters. Furthermore, our recent data demonstrated that the application of unilateral electrical stimulation is able to elicit bilateral hemodynamic responses in rat neocortex. 자료를 다운 받으시려면 아래의 링크을 클릭해주세요. http://physics.skku.ac.kr/ppt/090501.ppt
번호 제목 날짜 조회 수
공지 2021학년도 1학기 콜로퀴움 일정 2021.01.13 13671
공지 <12/8(Thu.) 11:00am>노벨상 소개 강연 - 2016년 노벨 물리학상: 위상 응집 물리의 탄생 2016.11.28 608566
634 <Mar.3(Wed.)>Scaling laws in Natural Language Processing 2021.02.25 164
633 <Feb.18(Thu.)> Hund's metallicity in the vicinity of a Van Hove singularity / Correlated topological phases in strongly correlated heterostructures 2021.02.16 471
632 <Jan.28(Thu.)>X-ray Absorption Spectroscopy Study of Amorphous Oxide Thin Films 2021.01.27 860
631 <Jan.14(Thu.)>Oxygen sponge effects for epitaxial manganite thin film design 2021.01.11 1512
630 <Dec.9(Wed.)>한국형 암흑물질 실험 2020.12.02 2076
629 <Dec.2(Wed.)>The era of gravitational waves, and the science that makes it possible 2020.11.25 2536
628 <Oct.14(Wed.)>New Ways to Search for the Dark World 2020.10.12 2821
627 <11/5(Thu.)> Higher Spin Cooper Pairs 2020.10.27 3301
626 <Sep.23(Wed.)>나는 내 마음이야 2020.09.16 3356
625 <Nov.18(Wed.)>When Physics meets the Living Cells 2020.11.11 3582
624 <Nov.4(Wed.)>Progresses in Elucidating the Optoelectronic Properties of Perovskite Semiconductor 2020.10.28 3674
623 <Oct.28(Wed.)> Physics of Global Warming 2020.10.22 3686
622 <Nov.11(Wed.)>Nonlinear optics to study charge, spin, and crystalline structures 2020.11.04 4209
621 <8/1(Sat.)> Recent Advances in Deep Learning 2020.07.29 4350
620 <Sep.16(Wed.)>Artificial Crystal 2020.09.14 4867
619 <Oct.7(Wed.)>Organic Photodiode for Image Sensor 2020.09.24 6725
618 <Dec.11(Wed.)>데이터 과학으로서의 물리학. 그리고 금융투자업 2019.12.04 17013
617 <12/10(Tue.)> Investigating dark matter signals at neutrino telescopes 2019.12.06 18832
616 <12/17(Tue.)> Nuclear spectroscopy with low energy reaction thermal neutrons in ILL 2019.12.17 19303