korean english


Home > 게시판 > 세미나

아래와 같이 콜로퀴움을 개최하오니 많이 참석해 주시기 바랍니다. 4시 10분부터 2층 라운지세미나실에 다과를 준비하오니 많은 참석 부탁드립니다 아 래 제목: In vivo optical imaging of hemodynamic changes as a surrogate signal of neuronal activity in the neocortex 연사: 서 민 아 교수(성균관대학교 생명과학과) 일시: 2009년 5월 1일(금) 오후4:30 장소: 물리학과 세미나실(31355호실) 초록: Optical imaging offers excellent spatio-temporal sensitivity that is unparalleled by any other perfusion based imaging techniques. We used in vivo optical recording of intrinsic signals (ORIS) to map neurovascular hemodynamics of perfusion, oximetry and membrane potential during epileptic events in rat and mouse neocortex. Studies of hemodynamic changes with ORIS alone were also performed in human. Laboratory studies in rodent epilepsy models have demonstrated a persistent increase in deoxygenated hemoglobin (Hbr) and a decrease in tissue oxygenation during interictal spikes and ictal events. This “epileptic dip”, like the “initial dip” recorded during normal sensory processing, implies that the enormous rise in cerebral blood flow (CBF) is inadequate to meet the increased metabolic demands associated with synchronized epileptic activity. These findings are critically important to the interpretation of the perfusion-based imaging studies, such as fMRI. In addition, we visualized the effect of direct cortical electrical stimulation, an alterative epilepsy treatment. The optical data following direct cortical electrical stimulation showed that hemodynamic signals are sensitive to different electrical stimulation parameters. Furthermore, our recent data demonstrated that the application of unilateral electrical stimulation is able to elicit bilateral hemodynamic responses in rat neocortex. 자료를 다운 받으시려면 아래의 링크을 클릭해주세요. http://physics.skku.ac.kr/ppt/090501.ppt
번호 제목 날짜 조회 수
공지 <12/8(Thu.) 11:00am>노벨상 소개 강연 - 2016년 노벨 물리학상: 위상 응집 물리의 탄생 2016.11.28 1078994
70 <5/28> The hunt for high energy neutrinos with IceCube - more evidence for their astrophysical origin 2014.05.22 112757
69 <11/13> Computer-Aided Engineering for Nucleic Acid Nanostructures 2013.11.07 113092
68 <5/21> Magnetism and Superconductivity 2014.05.14 113282
67 <3/26> Shedding infrared light on high-Tc superconductors 2014.03.19 113904
66 <Sep. 29(Wed.)> Longitudinal Spin Seebeck effect in Pt/YIG structure with monolayer WSe2 and MoS2 interlayer 2021.09.16 114544
65 <Nov. 8(Wed.) 4:30 PM> 연성물질 기반 위상학적 결함구조의 상전이와 응 2017.11.01 114721
64 <4/13> Introduction to Quantum Information Processing 2007.04.11 114962
63 <May 17(Wed.) 4:30 PM>Printed Electronics 2017.05.10 115009
62 <10/15> Electric control of magnetic nanostructures via spin torque 2010.10.08 115300
61 <5/14> Search for exotic materials: strongly correlated electron system 2010.05.10 116458
60 <12/4> The "Physics" of Climate Change 2009.12.02 118826
59 <3/26> Fractional Hall Physics of Epitaxial Graphene: 2010.03.19 121229
58 <3/31> ZnO nanorod heterostructures and nanodevices 2006.03.27 121252
57 <3/19> Bioconjugates of nanomaterials for biochip & biosensor applications 2010.03.16 125499
» <5/1>In vivo optical imaging of hemodynamic changes 2009.05.06 125904
55 <April.17(Wed.)> Emerging Artificial Synapse for Learning- and Energy-Efficient Neuromorphic System 2019.04.11 126232
54 <11/5> Modified nucleic acid systems for biomedical applications 2010.11.01 126641
53 <10/17> Graphitic Carbon Nanostructures 2008.10.27 127024
52 <12/3> Characteristic of risk asset in financial market. 2010.11.29 127859
51 <5/29> Nanomaterials Work at NASA-Johnson Space Center 2009.05.25 128188