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아 래
제목: Social Experience, Brain, and Behavior
연사: 송 자 경 박사(성균관대학교 생명과학과)
일시: 2009년 3월 27일(금) 오후4:30
장소: 물리학과 세미나실(31355호실)
초록: Crayfish (Procambarus clarkii) form dominance hierarchies, which are patterns of repeated fights
with expected outcomes of winner and loser. Establishment of hierarchies allows dominants the first
access to limited resources over subordinates, and leads to behavioral and cellular changes
corresponding to the social status. Here, the animals’ responses to an unexpected unilateral touch, a
non-social stimulus, were examined with respect to their social status and to their social context.
Isolates oriented to the stimulus source with raised claws and elevated posture. Dominants also
oriented to the stimulus both when tested alone and in the presence of a subordinate. Subordinates
oriented to the stimulus while separated from their familiar dominant partner; however, they avoided it
when tested while paired with the dominant. In subsequent tests first while semi-separated from the
dominant and later while fully separated, the same subordinates displayed more orienting responses
as the duration of
post-fight separation increased. These results suggest that the lingering effects of recent
social experience influence the behavior of subordinate animals.
During fights, crayfish release urine toward each other, providing critical chemosensory cues for
establishing hierarchies. Throughout the lifespan, new neuronal precursors are added into clusters of
olfactory local and projection interneurons (clusters 9 and 10). Here, the effect of pair-wise social
experience on neurogenesis in these brain regions was examined using the proliferation marker
bromodeoxyuridine. Groups of proliferating cells in clusters 9 and 10 formed distinctive comma shapes.
The BrdU-positive nuclei in the head part of the comma were smaller and more circular than those in
the tail part of the comma. Subordinates had fewer new neuronal precursors surviving in cluster 9 after
14 days than did dominants. Mitotic activity was not influenced by social status. The effect of social
experience on neurogenesis remained when the effect of body growth rate on neurogenesis was
removed. In conclusion, social domination enhances cell survival compared to social subordination.
Although the function of these surviving newborn neuronal precursors is unknown they may enhance
the learning ability of dominant crayfish.
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http://physics.skku.ac.kr/ppt/0327.ppt